Form: S-1

General form for registration of securities under the Securities Act of 1933

March 27, 2026

S-1 S-1 EX-FILING FEES 0001958777 FibroBiologics, Inc. N/A N/A 0001958777 2026-03-27 2026-03-27 0001958777 1 2026-03-27 2026-03-27 0001958777 2 2026-03-27 2026-03-27 0001958777 3 2026-03-27 2026-03-27 0001958777 4 2026-03-27 2026-03-27 0001958777 5 2026-03-27 2026-03-27 0001958777 6 2026-03-27 2026-03-27 0001958777 7 2026-03-27 2026-03-27 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-1

FibroBiologics, Inc.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Equity Common stock, par value $0.00001 per share ("Common Stock") 457(o) $ 5,000,000.00 0.0001381 $ 690.50
Fees to be Paid 2 Other Pre-funded warrants to purchase Common Stock Other 0.0001381 $ 0.00
Fees to be Paid 3 Equity Common Stock underlying pre-funded warrants 457(o) $ 0.00 0.0001381 $ 0.00
Fees to be Paid 4 Other Warrants to purchase Common Stock Other 0.0001381 $ 0.00
Fees to be Paid 5 Equity Common Stock underlying warrants 457(o) $ 5,000,000.00 0.0001381 $ 690.50
Fees to be Paid 6 Other Placement agent warrants to purchase Common Stock Other 0.0001381 $ 0.00
Fees to be Paid 7 Equity Common Stock underlying placement agent warrants 457(o) $ 437,500.00 0.0001381 $ 60.42
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities

Total Offering Amounts:

$ 10,437,500.00

$ 1,441.42

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 1,441.42

Offering Note

1

(1) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended (the "Securities Act"). (2) Pursuant to Rule 416 under the Securities Act, this Registration Statement on Form S-1 shall also cover an indeterminable number of additional shares of the registrant's securities that become issuable by reason of any stock splits, stock dividends or similar transactions.

2

(1) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended (the "Securities Act"). (3) The proposed maximum aggregate offering price of the Common Stock to be issued in the offering will be reduced on a dollar-for-dollar basis based on the offering price of any pre-funded warrants issued in the offering, and the proposed maximum aggregate offering price of the pre-funded warrants to be issued in the offering will be reduced on a dollar-for-dollar basis based on the offering price of any Common Stock issued in the offering. Accordingly, the proposed maximum aggregate offering price of the Common Stock and pre-funded warrants (including the Common Stock issuable upon exercise of the pre-funded warrants), if any, is $5,000,000. (4) No separate registration fee is payable pursuant to Rule 457(g) under the Securities Act.

3

(1) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended (the "Securities Act"). (3) The proposed maximum aggregate offering price of the Common Stock to be issued in the offering will be reduced on a dollar-for-dollar basis based on the offering price of any pre-funded warrants issued in the offering, and the proposed maximum aggregate offering price of the pre-funded warrants to be issued in the offering will be reduced on a dollar-for-dollar basis based on the offering price of any Common Stock issued in the offering. Accordingly, the proposed maximum aggregate offering price of the Common Stock and pre-funded warrants (including the Common Stock issuable upon exercise of the pre-funded warrants), if any, is $5,000,000.

4

(1) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended (the "Securities Act"). (4) No separate registration fee is payable pursuant to Rule 457(g) under the Securities Act.

5

(1) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended (the "Securities Act").

6

(1) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended (the "Securities Act"). (4) No separate registration fee is payable pursuant to Rule 457(g) under the Securities Act. (5) Represents warrants issuable to the placement agent, or its designees, to purchase a number of shares of Common Stock equal to 7.0% of the aggregate number of shares of Common Stock and/or pre-funded warrants being offered in this offering, at an exercise price equal to 125% of the combined public offering price per share of Common Stock and accompanying warrant.

7

(1) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended (the "Securities Act"). (5) Represents warrants issuable to the placement agent, or its designees, to purchase a number of shares of Common Stock equal to 7.0% of the aggregate number of shares of Common Stock and/or pre-funded warrants being offered in this offering, at an exercise price equal to 125% of the combined public offering price per share of Common Stock and accompanying warrant.

Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims
Fee Offset Sources
Rule 457(p)
Fee Offset Claims
Fee Offset Sources
Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date